Human STIM2 activation kit by CRISPRa

CAT#: GA111639

STIM2 CRISPRa kit - CRISPR gene activation of human stromal interaction molecule 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: STIM2
• Locus ID: 57620
• Kit Components:

  GA111639G1, STIM2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111639G2, STIM2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111639G3, STIM2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001169117, NM_001169118, NM_020860
• Synonyms: FLJ39527; KIAA1482
• Summary: This gene is a member of the stromal interaction molecule (STIM) family and likely arose, along with related family member STIM1, from a common ancestral gene. The encoded protein functions to regulate calcium concentrations in the cytosol and endoplasmic reticulum, and is involved in the activation of plasma membrane Orai Ca(2+) entry channels. This gene initiates translation from a non-AUG (UUG) start site. A signal peptide is cleaved from the resulting protein. Multiple transcript variants result from alternative splicing. [provided by RefSeq, Dec 2009]