Human PTBP2 activation kit by CRISPRa

CAT#: GA111753

PTBP2 CRISPRa kit - CRISPR gene activation of human polypyrimidine tract binding protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PTBP2
• Locus ID: 58155
• Kit Components:

  GA111753G1, PTBP2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111753G2, PTBP2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111753G3, PTBP2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001300985, NM_001300986, NM_001300987, NM_001300988, NM_001300989, NM_001300990, NM_021190, NR_125356, NR_125357
• Synonyms: brPTB; nPTB; PTBLP
• Summary: The protein encoded by this gene binds to intronic polypyrimidine clusters in pre-mRNA molecules and is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein (PTB) but most of its isoforms are expressed primarily in the brain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]