Human MASA (ENOPH1) activation kit by CRISPRa

CAT#: GA111765

ENOPH1 CRISPRa kit - CRISPR gene activation of human enolase-phosphatase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ENOPH1
• Locus ID: 58478
• Kit Components:

  GA111765G1, ENOPH1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111765G2, ENOPH1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111765G3, ENOPH1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001292017, NM_021204, NR_120457
• Synonyms: E1; MASA; MST145; mtnC
• Summary: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). [UniProtKB/Swiss-Prot Function]