Human Junctional Adhesion Molecule 2 (JAM2) activation kit by CRISPRa

CAT#: GA111777

JAM2 CRISPRa kit - CRISPR gene activation of human junctional adhesion molecule 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: JAM2
• Locus ID: 58494
• Kit Components:

  GA111777G1, JAM2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111777G2, JAM2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111777G3, JAM2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001270407, NM_001270408, NM_021219, NR_072999
• Synonyms: C21orf43; CD322; JAM-B; JAMB; PRO245; VE-JAM; VEJAM
• Summary: This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012]