Human ELOVL5 activation kit by CRISPRa

CAT#: GA111850

ELOVL5 CRISPRa kit - CRISPR gene activation of human ELOVL fatty acid elongase 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ELOVL5
• Locus ID: 60481
• Kit Components:

  GA111850G1, ELOVL5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111850G2, ELOVL5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111850G3, ELOVL5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001242828, NM_001242830, NM_001242831, NM_001301856, NM_021814
• Synonyms: dJ483K16.1; HELO1; SCA38
• Summary: This gene belongs to the ELO family. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum. This protein is involved in the elongation of long-chain polyunsaturated fatty acids. Mutations in this gene have been associated with spinocerebellar ataxia-38 (SCA38). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]