Human APOBEC3G activation kit by CRISPRa

CAT#: GA111856

APOBEC3G CRISPRa kit - CRISPR gene activation of human apolipoprotein B mRNA editing enzyme catalytic subunit 3G

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: APOBEC3G
• Locus ID: 60489
• Kit Components:

  GA111856G1, APOBEC3G gRNA vector 1 in pCas-Guide-CRISPRa

  GA111856G2, APOBEC3G gRNA vector 2 in pCas-Guide-CRISPRa

  GA111856G3, APOBEC3G gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_021822, NM_001349436, NM_001349437, NM_001349438, NR_146179
• Synonyms: A3G; ARCD; ARP-9; ARP9; bK150C2.7; CEM-15; CEM15; dJ494G10.1; MDS019
• Summary: This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene catalyzes site-specific deamination of both RNA and single-stranded DNA. The encoded protein has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity. [provided by RefSeq, Mar 2017]