Human BIGM103 (SLC39A8) activation kit by CRISPRa

CAT#: GA111985

SLC39A8 CRISPRa kit - CRISPR gene activation of human solute carrier family 39 member 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC39A8
• Locus ID: 64116
• Kit Components:

  GA111985G1, SLC39A8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA111985G2, SLC39A8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA111985G3, SLC39A8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001135146, NM_001135147, NM_001135148, NM_022154
• Synonyms: BIGM103; CDG2N; LZT-Hs6; PP3105; ZIP8
• Summary: This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Oct 2008]