Human SIL1 activation kit by CRISPRa

CAT#: GA112048

SIL1 CRISPRa kit - CRISPR gene activation of human SIL1 nucleotide exchange factor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SIL1
• Locus ID: 64374
• Kit Components:

  GA112048G1, SIL1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112048G2, SIL1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112048G3, SIL1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001037633, NM_022464
• Synonyms: BAP; MSS; ULG5
• Summary: This gene encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]