Human GRASP65 (GORASP1) activation kit by CRISPRa

CAT#: GA112104

GORASP1 CRISPRa kit - CRISPR gene activation of human golgi reassembly stacking protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GORASP1
• Locus ID: 64689
• Kit Components:

  GA112104G1, GORASP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112104G2, GORASP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112104G3, GORASP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001278789, NM_001278790, NM_031899, NR_103866, NR_103867
• Synonyms: GOLPH5; GRASP65; P65
• Summary: The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a membrane protein involved in establishing the stacked structure of the Golgi apparatus. It is a caspase-3 substrate, and cleavage of this encoded protein contributes to Golgi fragmentation in apoptosis. This encoded protein can form a complex with the Golgi matrix protein GOLGA2, and this complex binds to the vesicle docking protein p115. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]