Human XTP3TPA (DCTPP1) activation kit by CRISPRa

CAT#: GA112351

DCTPP1 CRISPRa kit - CRISPR gene activation of human dCTP pyrophosphatase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DCTPP1
• Locus ID: 79077
• Kit Components:

  GA112351G1, DCTPP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112351G2, DCTPP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112351G3, DCTPP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_024096, NR_134470, NR_134471
• Synonyms: CDA03; RS21C6; XTP3TPA
• Summary: The protein encoded by this gene is dCTP pyrophosphatase, which converts dCTP to dCMP and inorganic pyrophosphate. The encoded protein also displays weak activity against dTTP and dATP, but none against dGTP. This protein may be responsible for eliminating excess dCTP after DNA synthesis and may prevent overmethylation of CpG islands. Three transcript variants, one protein-coding and the other two non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2015]