Human MMP28 activation kit by CRISPRa

CAT#: GA112385

MMP28 CRISPRa kit - CRISPR gene activation of human matrix metallopeptidase 28

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MMP28
• Locus ID: 79148
• Kit Components:

  GA112385G1, MMP28 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112385G2, MMP28 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112385G3, MMP28 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001032278, NM_024302, NM_032950, NR_111988
• Synonyms: EPILYSIN; MM28; MMP-25; MMP-28; MMP25
• Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, such as asthma and metastasis. This gene encodes a secreted enzyme that degrades casein. Its expression pattern suggests that it plays a role in tissue homeostasis and in wound repair. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]