Human NEK11 activation kit by CRISPRa

CAT#: GA112682

NEK11 CRISPRa kit - CRISPR gene activation of human NIMA related kinase 11

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NEK11
• Locus ID: 79858
• Kit Components:

  GA112682G1, NEK11 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112682G2, NEK11 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112682G3, NEK11 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001146003, NM_001321220, NM_001321221, NM_001321222, NM_001321223, NM_001321224, NM_024800, NM_145910, NM_001353022, NM_001353023, NM_001353024, NM_001353025, NM_001353026, NM_001353027, NM_001353028, NM_001353029, NM_001353030, NM_001353031, NM_001353032, NM_001353033, NM_001353034, NM_001353036, NM_001353037, NM_001353038, NM_001353039, NM_001353040, NM_001353041, NM_001353042, NM_001353043, NM_001353044, NM_001353045, NM_001353046, NM_001353048
• Synonyms: FLJ23495
• Summary: This gene encodes a member of the never in mitosis gene A family of kinases. The encoded protein localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. The encoded protein appears to play roles in DNA replication and response to genotoxic stress. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]