Human GRPEL1 activation kit by CRISPRa

CAT#: GA112900

GRPEL1 CRISPRa kit - CRISPR gene activation of human GrpE like 1, mitochondrial

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GRPEL1
• Locus ID: 80273
• Kit Components:

  GA112900G1, GRPEL1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112900G2, GRPEL1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112900G3, GRPEL1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_025196
• Synonyms: HMGE
• Summary: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. [UniProtKB/Swiss-Prot Function]