Human ITIH5 activation kit by CRISPRa

CAT#: GA112972

ITIH5 CRISPRa kit - CRISPR gene activation of human inter-alpha-trypsin inhibitor heavy chain 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ITIH5
• Locus ID: 80760
• Kit Components:

  GA112972G1, ITIH5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112972G2, ITIH5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112972G3, ITIH5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001001851, NM_030569, NM_032817
• Synonyms: ITI-HC5; PP14776
• Summary: This gene encodes a heavy chain component of one of the inter-alpha-trypsin inhibitor (ITI) family members. ITI proteins are involved in extracellular matrix stabilization and in the prevention of tumor metastasis. They are also structurally related plasma serine protease inhibitors and are composed of a light chain and varying numbers of heavy chains. This family member is thought to function as a tumor suppressor in breast and thyroid cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]