Human sphingosine 1 phosphate phosphatase 1 (SGPP1) activation kit by CRISPRa

CAT#: GA113051

SGPP1 CRISPRa kit - CRISPR gene activation of human sphingosine-1-phosphate phosphatase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SGPP1
• Locus ID: 81537
• Kit Components:

  GA113051G1, SGPP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113051G2, SGPP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113051G3, SGPP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_030791
• Synonyms: SPPase1
• Summary: Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000 [PubMed 10859351]; Le Stunff et al., 2007 [PubMed 17895250]). [supplied by OMIM, Jun 2009]