Human CDT1 activation kit by CRISPRa

CAT#: GA113096

CDT1 CRISPRa kit - CRISPR gene activation of human chromatin licensing and DNA replication factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CDT1
• Locus ID: 81620
• Kit Components:

  GA113096G1, CDT1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113096G2, CDT1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113096G3, CDT1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_030928
• Synonyms: DUP; RIS2
• Summary: The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein. [provided by RefSeq, Mar 2011]