Human MED25 activation kit by CRISPRa

CAT#: GA113139

MED25 CRISPRa kit - CRISPR gene activation of human mediator complex subunit 25

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MED25
• Locus ID: 81857
• Kit Components:

  GA113139G1, MED25 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113139G2, MED25 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113139G3, MED25 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_030973
• Synonyms: ACID1; ARC92; CMT2B2; P78; PTOV2; TCBAP0758
• Summary: This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2. [provided by RefSeq, Apr 2010]