Human USP48 activation kit by CRISPRa

CAT#: GA113419

USP48 CRISPRa kit - CRISPR gene activation of human ubiquitin specific peptidase 48

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: USP48
• Locus ID: 84196
• Kit Components:

  GA113419G1, USP48 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113419G2, USP48 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113419G3, USP48 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001032730, NM_001330394, NM_032236, NM_001350164, NM_001350166, NM_001350167, NM_001350168
• Synonyms: RAP1GA1; USP31
• Summary: This gene encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin. Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]