Human PRAS40 (AKT1S1) activation kit by CRISPRa

CAT#: GA113527

AKT1S1 CRISPRa kit - CRISPR gene activation of human AKT1 substrate 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AKT1S1
• Locus ID: 84335
• Kit Components:

  GA113527G1, AKT1S1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113527G2, AKT1S1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113527G3, AKT1S1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001098632, NM_001098633, NM_001278159, NM_001278160, NM_032375
• Synonyms: Lobe; PRAS40
• Summary: AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]). [supplied by OMIM, Mar 2008]