Human L3MBTL3 activation kit by CRISPRa

CAT#: GA113558

L3MBTL3 CRISPRa kit - CRISPR gene activation of human L3MBTL histone methyl-lysine binding protein 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: L3MBTL3
• Locus ID: 84456
• Kit Components:

  GA113558G1, L3MBTL3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113558G2, L3MBTL3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113558G3, L3MBTL3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001007102, NM_032438, NM_001346550, NM_001346551
• Synonyms: MBT-1; MBT1
• Summary: This gene encodes a member of the malignant brain tumor (MBT) family of chromatin interacting transcriptional repressors. Members of this family function as methyl-lysine readers, which recognize methylated lysine residues on histone protein tails, and are associated with the repression of gene expression. The encoded protein may regulate hematopoiesis. Homozygous deletion of this gene has been observed in human patients with medulloblastoma. [provided by RefSeq, Oct 2016]