Human CBX2 activation kit by CRISPRa

CAT#: GA113678

CBX2 CRISPRa kit - CRISPR gene activation of human chromobox 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CBX2
• Locus ID: 84733
• Kit Components:

  GA113678G1, CBX2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113678G2, CBX2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113678G3, CBX2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005189, NM_032647
• Synonyms: CDCA6; M33; SRXY5
• Summary: This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2010]