Human ALG10 activation kit by CRISPRa

CAT#: GA113768

ALG10 CRISPRa kit - CRISPR gene activation of human ALG10 alpha-1,2-glucosyltransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ALG10
• Locus ID: 84920
• Kit Components:

  GA113768G1, ALG10 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113768G2, ALG10 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113768G3, ALG10 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_032834
• Synonyms: ALG10A; DIE2; KCR1
• Summary: This gene encodes a membrane-associated protein that adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. That is, it transfers the terminal glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc2Man9GlcNAc(2)-PP-Dol. The rat protein homolog was shown to specifically modulate the gating function of the rat neuronal ether-a-go-go (EAG) potassium ion channel. [provided by RefSeq, Jan 2010]