Human ZNRF1 activation kit by CRISPRa

CAT#: GA113782

ZNRF1 CRISPRa kit - CRISPR gene activation of human zinc and ring finger 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ZNRF1
• Locus ID: 84937
• Kit Components:

  GA113782G1, ZNRF1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113782G2, ZNRF1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113782G3, ZNRF1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_032268
• Synonyms: NIN283
• Summary: This gene encodes an E3 ubiquitin-protein ligase that plays a role in neural-cell differentiation. Overexpression of this gene causes neurite-like elongation. The encoded protein contains both a zinc finger and a RING finger motif and is localized in the endosome/lysosome compartment, indicating that it may be involved in ubiquitin-mediated protein modification, and in synaptic vessicle membranes in neurons. [provided by RefSeq, Feb 2012]