Human C19orf52 (TIMM29) activation kit by CRISPRa

CAT#: GA114037

TIMM29 CRISPRa kit - CRISPR gene activation of human translocase of inner mitochondrial membrane 29

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TIMM29
• Locus ID: 90580
• Kit Components:

  GA114037G1, TIMM29 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114037G2, TIMM29 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114037G3, TIMM29 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_138358
• Summary: Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force. Required for the stability of the TIM22 complex and functions in the assembly of the TIMM22 protein into the TIM22 complex. May facilitate cooperation between TIM22 and TOM complexes by interacting with TOMM40. [UniProtKB/Swiss-Prot Function]