Human IGSF8 activation kit by CRISPRa

CAT#: GA114271

IGSF8 CRISPRa kit - CRISPR gene activation of human immunoglobulin superfamily member 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IGSF8
• Locus ID: 93185
• Kit Components:

  GA114271G1, IGSF8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114271G2, IGSF8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114271G3, IGSF8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001206665, NM_052868, NM_001320247
• Synonyms: CD81P3; CD316; EWI-2; EWI2; KCT-4; LIR-D1; PGRL
• Summary: This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]