Human HSPC302 (TBCK) activation kit by CRISPRa

CAT#: GA114296

TBCK CRISPRa kit - CRISPR gene activation of human TBC1 domain containing kinase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TBCK
• Locus ID: 93627
• Kit Components:

  GA114296G1, TBCK gRNA vector 1 in pCas-Guide-CRISPRa

  GA114296G2, TBCK gRNA vector 2 in pCas-Guide-CRISPRa

  GA114296G3, TBCK gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001163435, NM_001163436, NM_001163437, NM_001290768, NM_033115
• Synonyms: HSPC302; IHPRF3; TBCKL
• Summary: This gene encodes a protein that contains a protein kinase domain, a Rhodanase-like domain and the Tre-2/Bub2/Cdc16 (TBC) domain. The encoded protein is thought to play a role in actin organization, cell growth and cell proliferation by regulating the mammalian target of the rapamycin (mTOR) signaling pathway. This protein may also be involved in the transcriptional regulation of the components of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]