Human SYTL5 activation kit by CRISPRa

CAT#: GA114334

SYTL5 CRISPRa kit - CRISPR gene activation of human synaptotagmin like 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SYTL5
• Locus ID: 94122
• Kit Components:

  GA114334G1, SYTL5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114334G2, SYTL5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114334G3, SYTL5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001163334, NM_001163335, NM_138780
• Synonyms: slp5
• Summary: The protein encoded by this gene belongs to the synaptotagmin-like (Slp) protein family, which contains a unique homology domain at the N-terminus, referred to as the Slp homology domain (SHD). The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of this gene is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]