Human FAM36A (COX20) activation kit by CRISPRa

CAT#: GA114578

COX20 CRISPRa kit - CRISPR gene activation of human cytochrome c oxidase assembly factor COX20

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: COX20
• Locus ID: 116228
• Kit Components:

  GA114578G1, COX20 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114578G2, COX20 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114578G3, COX20 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001312871, NM_001312872, NM_001312873, NM_001312874, NM_198076, NR_132419, NR_132420, NR_132421
• Synonyms: FAM36A
• Summary: This gene encodes a protein that plays a role in the assembly of cytochrome C oxidase, an important component of the respiratory pathway. It contains two transmembrane helices and localizes to the mitochondrial membrane. Mutations in this gene can cause mitochondrial complex IV deficiency, which results in ataxia and muscle hypotonia. There are multiple pseudogenes for this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]