Human Josephin 2 (JOSD2) activation kit by CRISPRa

CAT#: GA114916

JOSD2 CRISPRa kit - CRISPR gene activation of human Josephin domain containing 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: JOSD2
• Locus ID: 126119
• Kit Components:

  GA114916G1, JOSD2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA114916G2, JOSD2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA114916G3, JOSD2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001270639, NM_001270640, NM_001270641, NM_001270686, NM_138334
• Synonyms: SBBI54
• Summary: This gene encodes a protein containing a Josephin domain. Josephin domain-containing proteins are deubiquitinating enzymes which catalyze the hydrolysis of the bond between the C-terminal glycine of the ubiquitin peptide and protein substrates. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]