Human UBXD3 (UBXN10) activation kit by CRISPRa

CAT#: GA115014

UBXN10 CRISPRa kit - CRISPR gene activation of human UBX domain protein 10

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UBXN10
• Locus ID: 127733
• Kit Components:

  GA115014G1, UBXN10 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115014G2, UBXN10 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115014G3, UBXN10 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_152376
• Synonyms: UBXD3
• Summary: VCP/p97-binding protein required for ciliogenesis (PubMed:26389662). Acts as a tethering factor that facilitates recruitment of VCP/p97 to the intraflagellar transport complex B (IFT-B) in cilia (PubMed:26389662). UBX domain-containing proteins act as tethering factors for VCP/p97 and may specify substrate specificity of VCP/p97 (PubMed:26389662). [UniProtKB/Swiss-Prot Function]