Human SLITRK4 activation kit by CRISPRa

CAT#: GA115324

SLITRK4 CRISPRa kit - CRISPR gene activation of human SLIT and NTRK like family member 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLITRK4
• Locus ID: 139065
• Kit Components:

  GA115324G1, SLITRK4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115324G2, SLITRK4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115324G3, SLITRK4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001184749, NM_001184750, NM_173078
• Synonyms: DKFZp547M2010
• Summary: This gene encodes a transmembrane protein belonging to the the SLITRK family. These family members include two N-terminal leucine-rich repeat domains similar to those found in the axonal growth-controlling protein SLIT, as well as C-terminal regions similar to neurotrophin receptors. Studies of an homologous protein in mouse suggest that this family member functions to suppress neurite outgrowth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]