Human GCOM1 activation kit by CRISPRa

CAT#: GA115533

GCOM1 CRISPRa kit - CRISPR gene activation of human GRINL1A complex locus 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GCOM1
• Locus ID: 145781
• Kit Components:

  GA115533G1, GCOM1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115533G2, GCOM1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115533G3, GCOM1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001018090, NM_001018091, NM_001018092, NM_001018093, NM_001018094, NM_001018095, NM_001018096, NM_001018097, NM_001018098, NM_001018099, NM_001018101, NM_001285900, NR_104367, NR_104368, NR_104369, NR_104370, NR_104371
• Synonyms: gcom; Gcom2; GRINL1A; MYZAP; MYZAP-POLR2M
• Summary: This locus represents naturally occurring readthrough transcription between the neighboring MYZAP (myocardial zonula adherens protein) and POLR2M (polymerase (RNA) II (DNA directed) polypeptide M) genes on chromosome 15. Alternative splicing results in multiple readthrough transcript variants. Readthrough variants may encode proteins that share sequence identity with the upstream gene product or with both the upstream and downstream gene products. Some readthrough transcript variants are also expected to be candidates for nonsense-mediated decay (NMD). [provided by RefSeq, Oct 2013]