GCOM1 Human Gene Knockout Kit (CRISPR)

CAT#: KN422913

GCOM1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: GCOM1
• Locus ID: 145781
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001018090, NM_001018091, NM_001018092, NM_001018093, NM_001018094, NM_001018095, NM_001018096, NM_001018097, NM_001018098, NM_001018099, NM_001018101, NM_001285900, NR_104367, NR_104368, NR_104369, NR_104370, NR_104371
• Synonyms: gcom; Gcom2; GRINL1A; MYZAP; MYZAP-POLR2M
• Summary: This locus represents naturally occurring readthrough transcription between the neighboring MYZAP (myocardial zonula adherens protein) and POLR2M (polymerase (RNA) II (DNA directed) polypeptide M) genes on chromosome 15. Alternative splicing results in multiple readthrough transcript variants. Readthrough variants may encode proteins that share sequence identity with the upstream gene product or with both the upstream and downstream gene products. Some readthrough transcript variants are also expected to be candidates for nonsense-mediated decay (NMD). [provided by RefSeq, Oct 2013]