Human CCBE1 activation kit by CRISPRa

CAT#: GA115605

CCBE1 CRISPRa kit - CRISPR gene activation of human collagen and calcium binding EGF domains 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CCBE1
• Locus ID: 147372
• Kit Components:

  GA115605G1, CCBE1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115605G2, CCBE1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115605G3, CCBE1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_133459
• Synonyms: HKLLS1
• Summary: This gene is thought to function in extracellular matrix remodeling and migration. It is predominantly expressed in the ovary, but down regulated in ovarian cancer cell lines and primary carcinomas, suggesting its role as a tumour suppressor. Mutations in this gene have been associated with Hennekam lymphangiectasia-lymphedema syndrome, a generalized lymphatic dysplasia in humans. [provided by RefSeq, Mar 2010]