Human EXOC8 activation kit by CRISPRa

CAT#: GA115705

EXOC8 CRISPRa kit - CRISPR gene activation of human exocyst complex component 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EXOC8
• Locus ID: 149371
• Kit Components:

  GA115705G1, EXOC8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115705G2, EXOC8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115705G3, EXOC8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_175876
• Synonyms: EXO84; Exo84p; SEC84
• Summary: This gene encodes a component of the exocyst complex, an evolutionarily conserved multi-protein complex that plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. This protein is a target of activated Ral subfamily of GTPases and thereby regulates exocytosis by tethering vesicles to the plasma membrane. Mutations in this gene may be related to Joubert syndrome. [provided by RefSeq, Sep 2016]