Human WFDC5 activation kit by CRISPRa

CAT#: GA115723

WFDC5 CRISPRa kit - CRISPR gene activation of human WAP four-disulfide core domain 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: WFDC5
• Locus ID: 149708
• Kit Components:

  GA115723G1, WFDC5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115723G2, WFDC5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115723G3, WFDC5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_145652
• Synonyms: dJ211D12.5; PRG5; WAP1
• Summary: This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. Most WFDC proteins contain only one WFDC domain, and this encoded protein contains two WFDC domains. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. [provided by RefSeq, Jul 2008]