Human Cklfsf8 (CMTM8) activation kit by CRISPRa

CAT#: GA115827

CMTM8 CRISPRa kit - CRISPR gene activation of human CKLF like MARVEL transmembrane domain containing 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CMTM8
• Locus ID: 152189
• Kit Components:

  GA115827G1, CMTM8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA115827G2, CMTM8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA115827G3, CMTM8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001320308, NM_178868
• Synonyms: CKLFSF8; CKLFSF8-V2
• Summary: This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor, and plays a role in regulating the migration of tumor cells. The encoded protein is thought to function as a a negative regulator of epidermal growth factor-induced signaling. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]