Human ANO6 activation kit by CRISPRa

CAT#: GA116282

ANO6 CRISPRa kit - CRISPR gene activation of human anoctamin 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ANO6
• Locus ID: 196527
• Kit Components:

  GA116282G1, ANO6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA116282G2, ANO6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA116282G3, ANO6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001025356, NM_001142678, NM_001142679, NM_001142680, NM_001204803
• Synonyms: BDPLT7; SCTS; TMEM16F
• Summary: This gene encodes a multi-pass transmembrane protein that belongs to the anoctamin family. This protein is an essential component for the calcium-dependent exposure of phosphatidylserine on the cell surface. The scrambling of phospholipid occurs in various biological systems, such as when blood platelets are activated, they expose phosphatidylserine to trigger the clotting system. Mutations in this gene are associated with Scott syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]