Human RICTOR activation kit by CRISPRa

CAT#: GA116742

RICTOR CRISPRa kit - CRISPR gene activation of human RPTOR independent companion of MTOR complex 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RICTOR
• Locus ID: 253260
• Kit Components:

  GA116742G1, RICTOR gRNA vector 1 in pCas-Guide-CRISPRa

  GA116742G2, RICTOR gRNA vector 2 in pCas-Guide-CRISPRa

  GA116742G3, RICTOR gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001285439, NM_001285440, NM_152756
• Synonyms: AVO3; hAVO3; PIA
• Summary: RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]). [supplied by OMIM, Mar 2008]