Mouse Chrna7 activation kit by CRISPRa

CAT#: GA200034

Chrna7 CRISPRa kit - CRISPR gene activation of mouse cholinergic receptor, nicotinic, alpha polypeptide 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Chrna7
• Locus ID: 11441
• Kit Components:

  GA200034G1, Chrna7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200034G2, Chrna7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200034G3, Chrna7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007390
• Synonyms: Acra7; alpha7; nAchR
• Summary: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin. [UniProtKB/Swiss-Prot Function]