Mouse Asgr2 activation kit by CRISPRa

CAT#: GA200297

Asgr2 CRISPRa kit - CRISPR gene activation of mouse asialoglycoprotein receptor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Asgr2
• Locus ID: 11890
• Kit Components:

  GA200297G1, Asgr2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200297G2, Asgr2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200297G3, Asgr2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001313925, NM_001313926, NM_001313927, NM_007493
• Synonyms: ASGPR2; Asgr; Asgr-2; HL-2
• Summary: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene [provided by RefSeq, Sep 2015]