Mouse Neurod4 activation kit by CRISPRa

CAT#: GA200311

Neurod4 CRISPRa kit - CRISPR gene activation of mouse neurogenic differentiation 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Neurod4
• Locus ID: 11923
• Kit Components:

  GA200311G1, Neurod4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA200311G2, Neurod4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA200311G3, Neurod4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001329489, NM_001329490, NM_007501
• Synonyms: AI846749; ATH-3; Atoh3; bHLHa4; MATH-3; Math3
• Summary: This gene belongs to the neurogenic differentiation factor family and encodes a basic helix-loop-helix (bHLH) transcription factor which is expressed in the developing nervous system with high levels of expression in the brain, retina and cranial ganglions. Expression gradually becomes restricted to the neural retina. It is a key gene in the Ngn2-regulated neuronal differentiation pathway, coordinating the onset of cortical gene transcription. This gene also regulates amacrine cell fate determination in the retina. [provided by RefSeq, Jul 2016]