Mouse F2rl3 activation kit by CRISPRa

CAT#: GA201338

F2rl3 CRISPRa kit - CRISPR gene activation of mouse coagulation factor II (thrombin) receptor-like 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: F2rl3
• Locus ID: 14065
• Kit Components:

  GA201338G1, F2rl3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA201338G2, F2rl3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA201338G3, F2rl3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007975
• Synonyms: PAR4
• Summary: This gene encodes a member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Mice lacking a functional copy of this gene exhibit impaired platelet activation and prolonged bleeding times. [provided by RefSeq, Sep 2016]