Mouse Gabrg2 activation kit by CRISPRa

CAT#: GA201523

Gabrg2 CRISPRa kit - CRISPR gene activation of mouse gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol Gabrg2
Locus ID 14406
Kit Components

GA201523G1, Gabrg2 gRNA vector 1 in pCas-Guide-CRISPRa

GA201523G2, Gabrg2 gRNA vector 2 in pCas-Guide-CRISPRa

GA201523G3, Gabrg2 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_008073, NM_177408, NM_001362655, NM_001362656
Synonyms GABAA-R; Gabrg-2; gamma2
Summary This gene encodes a gamma-aminobutyric acid (GABA)-A receptor subunit, which is a member of the ligand-gated ion channel family. GABA is the major inhibitory neurotransmitter in the adult central nervous system, and conversely exhibits an excitatory function during development. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. This gene encodes one of three gamma subunits in mammals, which contain the binding site for benzodiazepine drugs. Several mutations in this gene are associated with epileptic seizures, and genetic knockdown is associated with anxiety behavior. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.