Mouse Hcfc1 activation kit by CRISPRa

CAT#: GA201855

Hcfc1 CRISPRa kit - CRISPR gene activation of mouse host cell factor C1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Hcfc1
• Locus ID: 15161
• Kit Components:

  GA201855G1, Hcfc1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA201855G2, Hcfc1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA201855G3, Hcfc1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_008224
• Synonyms: AW060991; HCF; HCF1
• Summary: This gene encodes a transcription cofactor that regulates the progression of cell cycle and maintain the ability of embryonic stem cells to self-renew. The encoded protein is a large precursor that undergoes site-specific proteolytic cleavage to yield N- and C-terminal chains that form a non-covalent heterodimer. The encoded protein has been implicated in the regulation of expression of immediate early genes after herpes simplex virus infection and glucose-stimulated secretion of insulin by pancreatic beta cells. [provided by RefSeq, Aug 2015]