Mouse Il18rap activation kit by CRISPRa

CAT#: GA202131

Il18rap CRISPRa kit - CRISPR gene activation of mouse interleukin 18 receptor accessory protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Il18rap
• Locus ID: 16174
• Kit Components:

  GA202131G1, Il18rap gRNA vector 1 in pCas-Guide-CRISPRa

  GA202131G2, Il18rap gRNA vector 2 in pCas-Guide-CRISPRa

  GA202131G3, Il18rap gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_010553
• Synonyms: AcPL; IL-1RAcPL; IL-18R-beta; IL-18RAcP; IL-18Rbeta
• Summary: Interleukin-18 (or interferon-gamma inducing factor) is a proinflammatory cytokine that induces cell-mediated immunity following microbial infection. This gene encodes a member of the interleukin-1 receptor family. The encoded protein is an accessory subunit of the receptor for interleukin-18 and mediates signaling through this cytokine. Mice lacking this gene exhibit a defective cell-mediated immune response. [provided by RefSeq, Jan 2014]