Mouse Kcna3 activation kit by CRISPRa

CAT#: GA202246

Kcna3 CRISPRa kit - CRISPR gene activation of mouse potassium voltage-gated channel, shaker-related subfamily, member 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Kcna3
• Locus ID: 16491
• Kit Components:

  GA202246G1, Kcna3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA202246G2, Kcna3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA202246G3, Kcna3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_008418
• Synonyms: Kca1-3; Kv1.3; Mk-3
• Summary: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. [UniProtKB/Swiss-Prot Function]