Mouse Krt16 activation kit by CRISPRa

CAT#: GA202370

Krt16 CRISPRa kit - CRISPR gene activation of mouse keratin 16

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Krt16
• Locus ID: 16666
• Kit Components:

  GA202370G1, Krt16 gRNA vector 1 in pCas-Guide-CRISPRa

  GA202370G2, Krt16 gRNA vector 2 in pCas-Guide-CRISPRa

  GA202370G3, Krt16 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001313958, NM_008470
• Synonyms: AI324768; CK-16; K16; Krt1-16
• Summary: The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The encoded protein is a cytokeratin and acts as an innate immune system effector, promoting the inflammatory response upon breach of the skin barrier. Defects in this gene are a cause of pachyonychia congenita. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]