Mouse Fxyd5 activation kit by CRISPRa

CAT#: GA203013

Fxyd5 CRISPRa kit - CRISPR gene activation of mouse FXYD domain-containing ion transport regulator 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Fxyd5
• Locus ID: 18301
• Kit Components:

  GA203013G1, Fxyd5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA203013G2, Fxyd5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA203013G3, Fxyd5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001111073, NM_001287213, NM_001287217, NM_008761
• Synonyms: EF-8; Oit2; RIC
• Summary: This gene encodes a precursor protein that is member of the FXYD family of transmembrane glycoproteins. Like most members of the FXYD family, the encoded protein is a subunit of the sodium-potassium adenosine triphosphatase pump. FXYD family members have tissue-specific expression and differentially regulate the activity of this pump. The protein encoded by this gene also plays a role in cell adhesion and motility. The orthologous human protein inhibits epithelial cadherin, a calcium-dependent adhesion protein and is associated with cancer (promotes metastasis). Alternative splicing of this mouse gene results in multiple transcript variants. [provided by RefSeq, Dec 2013]