Mouse Rab18 activation kit by CRISPRa

CAT#: GA203526

Rab18 CRISPRa kit - CRISPR gene activation of mouse RAB18, member RAS oncogene family

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Rab18
• Locus ID: 19330
• Kit Components:

  GA203526G1, Rab18 gRNA vector 1 in pCas-Guide-CRISPRa

  GA203526G2, Rab18 gRNA vector 2 in pCas-Guide-CRISPRa

  GA203526G3, Rab18 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001278447, NM_011225, NM_181070
• Synonyms: AA959686
• Summary: This gene encodes a member of the Ras-related small GTPases, which regulate membrane trafficking in organelles and transport vesicles. This protein is expressed predominantly in lipid droplets, organelles that store neutral lipids, and is proposed to play a role in lipolysis and lipogenesis. In humans mutations in this gene are associated with Warburg micro syndrome type 3. A pseudogene of this gene is located on chromosome X. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]